Evaluation of Altitude as an Independent Risk Factor for Mortality in Pediatric Acute Respiratory Distress Syndrome: Influence of Oxygenation, Ventilation, and Hospital Structure in a Multicenter Observational Study.
Status: Recruiting
Location: See all (4) locations...
Intervention Type: Other
Study Type: Observational
SUMMARY
This multicenter observational study will evaluate the association between geographic altitude, availability of critical care resources, and clinical outcomes in children with pediatric acute respiratory distress syndrome (PARDS). Data on demographics, physiology, and hospital structure will be collected from PICUs located at different altitudes worldwide. The study aims to identify gaps in PARDS management and provide recommendations adapted to diverse resource settings.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 1 month
Maximum Age: 18
Healthy Volunteers: f
View:
• Age between 1 month (corrected gestational age) and 18 years.
• Admission to a pediatric intensive care unit (PICU) or facility where mechanically ventilated children are cared for.
• Requirement of invasive mechanical ventilation.
• Diagnosis of pediatric acute respiratory distress syndrome (PARDS) according to PALICC criteria, confirmed within 24 hours before or after endotracheal intubation.
Locations
Other Locations
Colombia
Sociedad de Cirugia de Bogota Hospital de San Jose
RECRUITING
Bogotá
Clínica UROS S.A
RECRUITING
Neiva
Fundacion Hospital Infantil Los Angeles
RECRUITING
Pasto
Uruguay
Centro Hospitalario Pereira Rossell
RECRUITING
Montevideo
Contact Information
Primary
PABLO VASQUEZ-HOYOS, MD, MSc
pablovasquezmd@gmail.com
573187172029
Backup
SEBASTIAN GONZALEZ-DAMBRAUSKAS, MD
sgdambrauskas@gmail.com
59899585225
Time Frame
Start Date:2025-11-01
Estimated Completion Date:2028-03
Participants
Target number of participants:1600
Treatments
Low Altitude PICUs
Children with PARDS admitted to pediatric intensive care units located at altitudes between 0-1500 meters above sea level.
Intermediate Altitude PICUs
Children with PARDS admitted to pediatric intensive care units located at altitudes between 1501-2500 meters above sea level.
High Altitude PICUs
Children with PARDS admitted to pediatric intensive care units located at altitudes between 2501-3500 meters above sea level.
Very High Altitude PICUs
Children with PARDS admitted to pediatric intensive care units located at altitudes above 3500 meters above sea level.